Neuronal Activity Sheds Light on the Origin of Consciousness

neurosciencestuff:

Consciousness is everything people experience — from the taste of chocolate to the pain of a migraine, the disappointment of failing an exam to the thrill of holding a newborn baby. But the origin and nature of consciousness have puzzled scientists since antiquity.

A new Tel Aviv University study takes researchers a step closer to solving this mystery. The study, drawn from data collected by electrodes implanted in patients with epilepsy, identifies and measures the neural activity associated with a new conscious experience.

The research was led by Dr. Hagar Gelbard-Sagiv of TAU’s Sackler School of Medicine and Sagol School of Neuroscience, and the research team included Dr. Liad Mudrik of TAU’s School of Psychological Sciences and the Sagol School of Neuroscience, Michael Hill of UCLA, Prof. Christof Koch of the Allen Institute for Brain Science and Prof. Itzhak Fried of TAU’s Sackler School of Medicine and UCLA. Lab work and clinical research for the study were conducted at TAU, UCLA, the Tel Aviv Sourasky Medical Center and Caltech Institute of Technology. The study was published in Nature Communications.

“Computers and robots interact with the world without being conscious. But something miraculous happens inside our brains to make us conscious and experience the world from a subjective perspective,” said Dr. Gelbard-Sagiv. “Despite 30 years of neuroscientific research in this area, we still do not know which areas of the brain take part in the process.

“Our new study brings us one step closer to understanding consciousness and conscious experience at the most concrete level: the electrical activity of individual neurons.”

Because the conscious experience is private and inaccessible to observers, it is mostly studied in people who are capable of reporting their subjective experiences. Moreover, researchers are often limited to indirect measures of brain activity, such as EEG and fMRI. Here, the researchers took advantage of a unique medical opportunity: the surgical implantation of electrodes in the brains of patients with epilepsy to determine the precise areas responsible for their seizures. Patients were monitored for a week or two, until enough data on their seizures had been collected. During this time, the implanted electrodes recorded the activity of individual neurons in their vicinity.

The researchers presented two different images to the patient, one to each eye, to probe the moment in which a new experience arises. For example: An image of a house was presented to the right eye and an image of a face to the left eye. In this situation, known as “binocular rivalry,” the brain cannot combine the two images. Instead, the subject sees either the house or the face, and this alternates irregularly every few seconds. These alternations happened involuntarily, while the physical stimulus remained constant. This allowed researchers to isolate brain activity related to the change in perception and differentiate it from brain activity related to the physical stimulus.

The scientists discovered that the activity in frontal lobe neurons changed almost two seconds before the patient reported an alternation in perception, and that the neuronal activity in the medial temporal lobe changed one second before a report.

“Two seconds is a long time in terms of neural activity,” Dr. Gelbard-Sagiv said. “We believe that the activity of these neurons not only correlates with perception, but also may take part in the process that leads to the emergence of a conscious percept.”

“The study captures individual cells in the human brain just before one conscious experience is replaced by another,” Prof. Fried said. “It is a unique privilege to gain such a rare glimpse into human consciousness. At the same time, we can provide clinical care aimed at alleviating severe epilepsy in our patients.”

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velvet-worm:

i just wanted to help him make a good game (×﹏×)

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nicoandninerss:

How do we know that two and two make four? Or that the force of gravity works? Or that the past is unchangeable? If both the past and the external world exist in the mind, and the mind itself is controllable, what then? -George Orwell

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nitrostreak:
“ stability:
“I wish i would’ve thought of this when I was in school
”
That’s the most Chaotic Neutral Parent thing I’ve ever heard
”

nitrostreak:

stability:

I wish i would’ve thought of this when I was in school

That’s the most Chaotic Neutral Parent thing I’ve ever heard

103,503 notes

souliloquyyy:
“OC Moodboard ~ Omega v2.0
”
Reblog for the well placed Radiohead lyric.

souliloquyyy:

OC Moodboard ~ Omega v2.0

Reblog for the well placed Radiohead lyric.

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stank-sinatra:

bandersnatch // donnie darko

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Do you like the color of the sky :D

such-justice-wow:

tyson-ot-nw:

qsy-draws-a-lot:

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you better watch out

You better watch out

You Better Watch Out

You Better WATCH OUT

YOU BETTER WATCH OUT

YOU BETTER WATCH OUT

YOU BETTER WATCH OUT

YOU BETTER WATCH OUT

YOU BETTER WATCH OUT!

I do not like the colour of this sky

65,155 notes

gal-gadot:

Sorry, mate. Wrong path.

Black Mirror: Bandersnatch (2018) dir. David Slade.  

4,486 notes

moiseszy:

Voight-Kampff Test 

Blade Runner (1982)

The “Voight-Kampff” Test is designed to distinguish androids from humans.

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hotmess–inasundress:

My goal for 2019 is to be as happy as people pretend to be on social media

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societysarmageddon:

Honestly I find myself thinking about things too much when I’m back here visiting. There are so many memories and a few close friends I really wish I could take back with me. I miss the clean air and year round flowers and cool 70 degree days already. There is one person in particular who has been on my mind before and even more so now but I can’t help but feel it’s a pipe dream. I mean from a cognitive and psychological perspective I’m sure I’m missing the concept of a caring and honest relationship and empathasizing with the bad news. However I also know how awful it feels to be where they are now and I’d be lying if I said I hadnt considered how things would have been if they followed through the last time they were going to leave. It has been years since I was in that situation. When you date someone for so long you define your future, yourself, and your plans around a we instead of me. It’s the little things that slowly begin to numb you though. There are entire albums I can’t listen to, and stupid little phrases or reactions to things I see that they would like. I know all of this is in store for her too, and I wish I could help but I know she keeps her walls up.

Apart from these bombarding thoughts all the other plans I had fell through, some with literally no explaination, just literally no response after asking if I wanted to do dinner. If you ever want to easily know who your real friends are and who is just a fairweather friend, just leave for a year or more and see who notices your absence.

I know I drove some of my good friends crazy with all the stories of my success in my career and move, but honestly money and success only fulfill half of what I need from life and the lack of balance in this regard often keeps me awake at night.

So three years have passed but sometimes it seems as if nothing has really changed. Somehow the person this post was about has managed to make it to the same three year mark I did. I never realized just how alike our situations were. Everything about new years just took me right back to when I was in her shoes, and I wish I could just hug her and tell her that things will be better, but I already know how this sordid tale will end for her. Things have progressed to the point where the gas lighting has reached talks of marriage, and I don’t know if she will be strong enough to make the decision she needs to…

It really isn’t like me to rant like this but I’m in a weird place myself these days I guess. “Just tell him that he is right and apologize” After three years of doing just that myself, my heart truly feels for you at this point. I couldn’t help but question if I was really just some observer watching you suffer in your own private hell. We have mastered the art of speaking without words, of holding two conversations where only the subtext matters, of speaking with our eyes alone.

“I’m a control freak” he brags, the stench of booze heavy on his breath, while somehow ironically explaining to me the meaning behind a tattoo that is supposed to be about yin and yang, about balance. He brags about a history of sports while shrugging off a random comments about seizures. The symptoms of substance abuse, trauma, and brain damage clear to those who can see. He thought that if he could win us over that he would have our blessing. The approval of those who “know you better than him” apparently. He told me that you weren’t going to come until you heard that I was there with a nervous look in his eye.

“Merry Christmas” he says, anything to gaslight you by saying the word “marry” to your family. “Bye dad” he says, desperate to show his place in your life, to reassure himself that you are his. He wants to ask for your fathers permission, but doesn’t understand how that objectification could upset you. I was only partially kidding when I said I would make a counter dowry offer if he wanted to do things like that. I know that when he brings up marriage your heart stops as part of you realizes that would make all of this permanent. It was just last year that you told me you didn’t see a future there. And how could we forget the wedding?

He grabs a cigarette and smokes it while dancing to a playlist you personally curated just to make him happy. Each song tied to a previously happy memory, but each lyric laced with a bitter warning that he was incapable of noticing. As I watched him put out his cigarette, I thought that would be the final wakeup call for you. I delighted at the chance to remind him, that you were the one that guilted me into finally kicking the habit for good. I’ll never forget the look of disappointment in your eyes three years ago when I thought about lighting a cigarette. Cheers to the fact we’ve both succeeded on that at least.

You told him to leave, you told him to stop, you told him no, you asked him to stop being all handsy, you asked me for my help, but how could I do it for you when you keep crawling back to him at every chance? As long as you continue to tell yourself that things are fine, as long as you go out of your way to document and record only the good moments, to edit your own memories, to let him tell you what to think and feel, how can I make that decision for you? There are two principles I strive to live by. I never lie, I will always be true. I value freewill, I can only show you a different path to the one you are on, all things worth fighting for in life take some faith. Sometimes I wish I didn’t stand so true to those values though, I spend too much time thinking what could have been if I spoke a little louder, if I wore my heart on my sleeve, if I laid out all the pieces for all to see and prayed that reason would prevail. What would have happened if you stayed? If you refused to leave with him? What if we had an honest conversation without any metaphors or interruptions? Some things I guess will keep remaining what if’s.

You asked me if I was taking care of myself, I said for the most part…but if I’m being honest with myself, I’ve been feeling a bit dead inside. It has been far too long since I’ve felt adored, had butterflies, or didn’t feel alone. We both have a bad habit of looking to others to show our value in this world. We care more about the happiness of others, at the cost of our own. You wanted to know how I finally got the strength to leave? At some point I just realized there was no good that could come from a parasitic relationship. I literally almost died, and she was more concerned I couldn’t celebrate her birthday when I was in the hospital. Even then I couldn’t leave. Then one day we had a fight, and like you I said no, I asked her to leave, the difference is I didn’t give in to the guilt trip and false promises that time. I accepted the possibility of a life of loneliness, I moved across the country and allowed myself to be swallowed whole by my work. I relearned what it is to be an “I” and not a “We”. I accepted that in life, you can’t change what was, but you can control the narrative, for better and for worse. Life always seems to give me reason to believe that everything, no matter how trivial has a purpose, something for us to learn, something that must mold us in preparation for greater things in life to come. The person I am now is not the person I was then. I’ve gained a level of patience and understanding that most have no need for. I’ve learned to see past the superficial facade that people put up, because I have come to understand just how fragile that tailored image presented to the world truly is. I’ve learned that if I’m important enough to someone, then they will reach out to me. I learned that I shouldn’t have to dedicate myself solely to the needs of others who refuse to help themselves or listen to reason.

Part of my visit this year was to give some thought to where I want to be in life. I thought that perhaps I’d be happier if I moved back, but the longer I stay here the more I realize that there weren’t many people in my life here that were true friends or fully understood me as a person or how I see the world. I’ve come to realize I’d rather grow with someone in pursuit of true happiness and truth, than carry on with appearances, social media, and the concept or idea of someone. I wonder how different things would be if I never left here, but I couldn’t imagine my life having the same range of opportunities if I hadn’t left that relationship, or this state, when I did.

I know someday we will have that dance you owe me, the only question I have at this point is, on what terms?

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